SWI/SNF-INDEPENDENT NUCLEASE HYPERSENSITIVITY AND INCREASED HISTONE ACETYLATION AT THE P1 PROMOTER ACCOMPANY ACTIVE TRANSCRIPTION OF THE BONE MASTER GENE RUNX2

The Runx2 transcription factor is essential for skeletal development as it regulates expression of several key bone-related genes. Multiple lines of evidence indicate that expression of the Runx2/p57 isoform in osteoblasts is controlled by the distal P1 promoter. Alterations of chromatin structure a...

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Bibliografiset tiedot
Päätekijät: Cruzat, Fernando, Henriquez, Berta, Villagra, Alejandro, Hepp, Matias, Lian, Jane B., van Wijnen, Andre J., Stein, Janet L., Imbalzano, Anthony N., Stein, Gary S., Montecino, Martin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760825/
https://ncbi.nlm.nih.gov/pubmed/19545172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9004792
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