SWI/SNF-INDEPENDENT NUCLEASE HYPERSENSITIVITY AND INCREASED HISTONE ACETYLATION AT THE P1 PROMOTER ACCOMPANY ACTIVE TRANSCRIPTION OF THE BONE MASTER GENE RUNX2

The Runx2 transcription factor is essential for skeletal development as it regulates expression of several key bone-related genes. Multiple lines of evidence indicate that expression of the Runx2/p57 isoform in osteoblasts is controlled by the distal P1 promoter. Alterations of chromatin structure a...

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Hlavní autoři: Cruzat, Fernando, Henriquez, Berta, Villagra, Alejandro, Hepp, Matias, Lian, Jane B., van Wijnen, Andre J., Stein, Janet L., Imbalzano, Anthony N., Stein, Gary S., Montecino, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760825/
https://ncbi.nlm.nih.gov/pubmed/19545172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9004792
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