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Fibroblast growth factor rescues brain endothelial cells lacking presenilin 1 from apoptotic cell death following serum starvation

Presenilin 1 (Psen1) is important for vascular brain development and is known to influence cellular stress responses. To understand the role of Psen1 in endothelial stress responses, we investigated the effects of serum withdrawal on wild type (wt) and Psen1−/− embryonic brain endothelial cells. Ser...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gama Sosa, Miguel A., De Gasperi, Rita, Hof, Patrick R., Elder, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957214/
https://ncbi.nlm.nih.gov/pubmed/27443835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30267
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