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Fibroblast growth factor rescues brain endothelial cells lacking presenilin 1 from apoptotic cell death following serum starvation

Presenilin 1 (Psen1) is important for vascular brain development and is known to influence cellular stress responses. To understand the role of Psen1 in endothelial stress responses, we investigated the effects of serum withdrawal on wild type (wt) and Psen1−/− embryonic brain endothelial cells. Ser...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Gama Sosa, Miguel A., De Gasperi, Rita, Hof, Patrick R., Elder, Gregory A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957214/
https://ncbi.nlm.nih.gov/pubmed/27443835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30267
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