Fibroblast growth factor rescues brain endothelial cells lacking presenilin 1 from apoptotic cell death following serum starvation

Presenilin 1 (Psen1) is important for vascular brain development and is known to influence cellular stress responses. To understand the role of Psen1 in endothelial stress responses, we investigated the effects of serum withdrawal on wild type (wt) and Psen1−/− embryonic brain endothelial cells. Ser...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Gama Sosa, Miguel A., De Gasperi, Rita, Hof, Patrick R., Elder, Gregory A.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957214/
https://ncbi.nlm.nih.gov/pubmed/27443835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30267
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