A carregar...
Cortical Development in the Presenilin-1 Null Mutant Mouse Fails After Splitting of the Preplate and is Not Due to a Failure of Reelin-Dependent Signaling
Cortical development is disrupted in presenilin-1 null mutant (Psen1−/−) mice. Prior studies have commented on similarities between Psen1−/− and reeler mice. Reelin induces phosphorylation of Dab1 and activates the phosphatidylinositol 3-kinase (PI3K)/Akt pathway. Psen1 is known to modulate PI3K/Akt...
Na minha lista:
| Main Authors: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2566957/ https://ncbi.nlm.nih.gov/pubmed/18729224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21661 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|