Extracellular Cl(−) regulates human SO(4)(2−)/anion exchanger SLC26A1 by altering pH-sensitivity of anion transport

Genetic deficiency of the SLC26A1 anion exchanger in mice is known to be associated with hyposulfatemia and hyperoxaluria with nephrolithiasis, but many aspects of human SLC26A1 function remain to be explored. We report here the functional characterization of human SLC26A1, a DIDS-sensitive, electro...

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Bibliographic Details
Published in:Pflugers Arch
Main Authors: Wu, Meng, Heneghan, John F., Vandorpe, David H., Escobar, Laura I., Wu, Bai-Lin, Alper, Seth L.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956541/
https://ncbi.nlm.nih.gov/pubmed/27125215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-016-1823-8
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