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Extracellular Cl(−) regulates human SO(4)(2−)/anion exchanger SLC26A1 by altering pH-sensitivity of anion transport

Genetic deficiency of the SLC26A1 anion exchanger in mice is known to be associated with hyposulfatemia and hyperoxaluria with nephrolithiasis, but many aspects of human SLC26A1 function remain to be explored. We report here the functional characterization of human SLC26A1, a DIDS-sensitive, electro...

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Détails bibliographiques
Publié dans:Pflugers Arch
Auteurs principaux: Wu, Meng, Heneghan, John F., Vandorpe, David H., Escobar, Laura I., Wu, Bai-Lin, Alper, Seth L.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956541/
https://ncbi.nlm.nih.gov/pubmed/27125215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-016-1823-8
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