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Species differences in Cl(−) affinity and in electrogenicity of SLC26A6-mediated oxalate/Cl(−) exchange correlate with the distinct human and mouse susceptibilities to nephrolithiasis
The mouse is refractory to lithogenic agents active in rats and humans, and so has been traditionally considered a poor experimental model for nephrolithiasis. However, recent studies have identified slc26a6 as an oxalate nephrolithiasis gene in the mouse. Here we extend our earlier demonstration of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375677/ https://ncbi.nlm.nih.gov/pubmed/18174209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.143222 |
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