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Extracellular Cl(−) regulates human SO(4)(2−)/anion exchanger SLC26A1 by altering pH-sensitivity of anion transport

Genetic deficiency of the SLC26A1 anion exchanger in mice is known to be associated with hyposulfatemia and hyperoxaluria with nephrolithiasis, but many aspects of human SLC26A1 function remain to be explored. We report here the functional characterization of human SLC26A1, a DIDS-sensitive, electro...

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書誌詳細
出版年:Pflugers Arch
主要な著者: Wu, Meng, Heneghan, John F., Vandorpe, David H., Escobar, Laura I., Wu, Bai-Lin, Alper, Seth L.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956541/
https://ncbi.nlm.nih.gov/pubmed/27125215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-016-1823-8
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