Native and recombinant Slc26a3 (downregulated in adenoma, Dra) do not exhibit properties of 2Cl(−)/1HCO(3)(−) exchange

The recent proposal that Dra/Slc26a3 mediates electrogenic 2Cl(−)/1HCO(3)(−) exchange suggests a required revision of classical concepts of electroneutral Cl(−) transport across epithelia such as the intestine. We investigated 1) the effect of endogenous Dra Cl(−)/HCO(3)(−) activity on apical membra...

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Bibliographische Detailangaben
Hauptverfasser: Alper, Seth L., Stewart, Andrew K., Vandorpe, David H., Clark, Jeffrey S., Zachary Horack, R., Simpson, Janet E., Walker, Nancy M., Clarke, Lane L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2011
Schlagworte:
Membrane Transporters, Ion Channels and Pumps
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043631/
https://ncbi.nlm.nih.gov/pubmed/21068358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00366.2010
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