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Dynein Light Intermediate Chain 2 Facilitates the Metaphase to Anaphase Transition by Inactivating the Spindle Assembly Checkpoint

The multi-functional molecular motor cytoplasmic dynein performs diverse essential roles during mitosis. The mechanistic importance of the dynein Light Intermediate Chain homologs, LIC1 and LIC2 is unappreciated, especially in the context of mitosis. LIC1 and LIC2 are believed to exist in distinct c...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Mahale, Sagar P., Sharma, Amit, Mylavarapu, Sivaram V. S.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956306/
https://ncbi.nlm.nih.gov/pubmed/27441562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159646
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