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Dynein Light Intermediate Chain 2 Facilitates the Metaphase to Anaphase Transition by Inactivating the Spindle Assembly Checkpoint

The multi-functional molecular motor cytoplasmic dynein performs diverse essential roles during mitosis. The mechanistic importance of the dynein Light Intermediate Chain homologs, LIC1 and LIC2 is unappreciated, especially in the context of mitosis. LIC1 and LIC2 are believed to exist in distinct c...

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發表在:PLoS One
Main Authors: Mahale, Sagar P., Sharma, Amit, Mylavarapu, Sivaram V. S.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956306/
https://ncbi.nlm.nih.gov/pubmed/27441562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159646
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