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Mad2-independent Spindle Assembly Checkpoint Activation and Controlled Metaphase–Anaphase Transition in Drosophila S2 Cells

The spindle assembly checkpoint is essential to maintain genomic stability during cell division. We analyzed the role of the putative Drosophila Mad2 homologue in the spindle assembly checkpoint and mitotic progression. Depletion of Mad2 by RNAi from S2 cells shows that it is essential to prevent mi...

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Detaylı Bibliyografya
Asıl Yazarlar: Orr, Bernardo, Bousbaa, Hassan, Sunkel, Claudio E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Cell Biology 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805101/
https://ncbi.nlm.nih.gov/pubmed/17182852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-07-0587
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