Cdk1-mediated DIAPH1 phosphorylation maintains metaphase cortical tension and inactivates the spindle assembly checkpoint at anaphase

Animal cells undergo rapid rounding during mitosis, ensuring proper chromosome segregation, during which an outward rounding force abruptly increases upon prometaphase entry and is maintained at a constant level during metaphase. Initial cortical tension is generated by the actomyosin system to whic...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Nishimura, Koutarou, Johmura, Yoshikazu, Deguchi, Katashi, Jiang, Zixian, Uchida, Kazuhiko S. K., Suzuki, Narumi, Shimada, Midori, Chiba, Yoshie, Hirota, Toru, Yoshimura, Shige H., Kono, Keiko, Nakanishi, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6395754/
https://ncbi.nlm.nih.gov/pubmed/30816115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08957-w
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