Cdk1-mediated DIAPH1 phosphorylation maintains metaphase cortical tension and inactivates the spindle assembly checkpoint at anaphase

Animal cells undergo rapid rounding during mitosis, ensuring proper chromosome segregation, during which an outward rounding force abruptly increases upon prometaphase entry and is maintained at a constant level during metaphase. Initial cortical tension is generated by the actomyosin system to whic...

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Vydáno v:Nat Commun
Hlavní autoři: Nishimura, Koutarou, Johmura, Yoshikazu, Deguchi, Katashi, Jiang, Zixian, Uchida, Kazuhiko S. K., Suzuki, Narumi, Shimada, Midori, Chiba, Yoshie, Hirota, Toru, Yoshimura, Shige H., Kono, Keiko, Nakanishi, Makoto
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6395754/
https://ncbi.nlm.nih.gov/pubmed/30816115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08957-w
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