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The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle Orientation

Cytoplasmic dynein 1 is a multi-protein intracellular motor essential for mediating several mitotic functions, including the establishment of proper spindle orientation. The functional relevance and mechanistic distinctions between two discrete dynein subpopulations distinguished only by Light Inter...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mahale, Sagar, Kumar, Megha, Sharma, Amit, Babu, Aswini, Ranjan, Shashi, Sachidanandan, Chetana, Mylavarapu, Sivaram V. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431351/
https://ncbi.nlm.nih.gov/pubmed/28003657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-016-0030-3
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