Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly

Mitotic spindle formation and chromosome segregation depend critically on kinetochore–microtubule (KT–MT) interactions. A new protein, termed Spindly in Drosophila and SPDL-1 in C. elegans, was recently shown to regulate KT localization of dynein, but depletion phenotypes revealed striking differenc...

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Bibliographic Details
Main Authors: Chan, Ying Wai, Fava, Luca L., Uldschmid, Andreas, Schmitz, Michael H.A., Gerlich, Daniel W., Nigg, Erich A., Santamaria, Anna
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2009
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711594/
https://ncbi.nlm.nih.gov/pubmed/19468067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200812167
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