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Apoptotic Activity of MeCP2 Is Enhanced by C-Terminal Truncating Mutations

Methyl-CpG binding protein 2 (MeCP2) is a widely abundant, multifunctional protein most highly expressed in post-mitotic neurons. Mutations causing Rett syndrome and related neurodevelopmental disorders have been identified along the entire MECP2 locus, but symptoms vary depending on mutation type a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Williams, Alison A., Mehler, Vera J., Mueller, Christina, Vonhoff, Fernando, White, Robin, Duch, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956225/
https://ncbi.nlm.nih.gov/pubmed/27442528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159632
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