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Drosophila as a Model for MECP2 Gain of Function in Neurons
Methyl-CpG-binding protein 2 (MECP2) is a multi-functional regulator of gene expression. In humans loss of MECP2 function causes classic Rett syndrome, but gain of MECP2 function also causes mental retardation. Although mouse models provide valuable insight into Mecp2 gain and loss of function, the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3283685/ https://ncbi.nlm.nih.gov/pubmed/22363746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031835 |
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