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Drosophila as a Model for MECP2 Gain of Function in Neurons

Methyl-CpG-binding protein 2 (MECP2) is a multi-functional regulator of gene expression. In humans loss of MECP2 function causes classic Rett syndrome, but gain of MECP2 function also causes mental retardation. Although mouse models provide valuable insight into Mecp2 gain and loss of function, the...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Vonhoff, Fernando, Williams, Alison, Ryglewski, Stefanie, Duch, Carsten
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283685/
https://ncbi.nlm.nih.gov/pubmed/22363746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031835
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