Lipodystrophy Due to Adipose Tissue–Specific Insulin Receptor Knockout Results in Progressive NAFLD

Ectopic lipid accumulation in the liver is an almost universal feature of human and rodent models of generalized lipodystrophy and is also a common feature of type 2 diabetes, obesity, and metabolic syndrome. Here we explore the progression of fatty liver disease using a mouse model of lipodystrophy...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Diabetes
Autori principali: Softic, Samir, Boucher, Jeremie, Solheim, Marie H., Fujisaka, Shiho, Haering, Max-Felix, Homan, Erica P., Winnay, Jonathon, Perez-Atayde, Antonio R., Kahn, C. Ronald
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2016
Soggetti:
Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955986/
https://ncbi.nlm.nih.gov/pubmed/27207510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0213
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