Lipodystrophy Due to Adipose Tissue–Specific Insulin Receptor Knockout Results in Progressive NAFLD

Ectopic lipid accumulation in the liver is an almost universal feature of human and rodent models of generalized lipodystrophy and is also a common feature of type 2 diabetes, obesity, and metabolic syndrome. Here we explore the progression of fatty liver disease using a mouse model of lipodystrophy...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Softic, Samir, Boucher, Jeremie, Solheim, Marie H., Fujisaka, Shiho, Haering, Max-Felix, Homan, Erica P., Winnay, Jonathon, Perez-Atayde, Antonio R., Kahn, C. Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2016
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955986/
https://ncbi.nlm.nih.gov/pubmed/27207510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0213
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