Lipodystrophy Due to Adipose Tissue–Specific Insulin Receptor Knockout Results in Progressive NAFLD

Ectopic lipid accumulation in the liver is an almost universal feature of human and rodent models of generalized lipodystrophy and is also a common feature of type 2 diabetes, obesity, and metabolic syndrome. Here we explore the progression of fatty liver disease using a mouse model of lipodystrophy...

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發表在:Diabetes
Main Authors: Softic, Samir, Boucher, Jeremie, Solheim, Marie H., Fujisaka, Shiho, Haering, Max-Felix, Homan, Erica P., Winnay, Jonathon, Perez-Atayde, Antonio R., Kahn, C. Ronald
格式: Artigo
語言:Inglês
出版: American Diabetes Association 2016
主題:
Metabolism
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955986/
https://ncbi.nlm.nih.gov/pubmed/27207510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0213
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