Lipodystrophy Due to Adipose Tissue–Specific Insulin Receptor Knockout Results in Progressive NAFLD

Ectopic lipid accumulation in the liver is an almost universal feature of human and rodent models of generalized lipodystrophy and is also a common feature of type 2 diabetes, obesity, and metabolic syndrome. Here we explore the progression of fatty liver disease using a mouse model of lipodystrophy...

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Dades bibliogràfiques
Publicat a:Diabetes
Autors principals: Softic, Samir, Boucher, Jeremie, Solheim, Marie H., Fujisaka, Shiho, Haering, Max-Felix, Homan, Erica P., Winnay, Jonathon, Perez-Atayde, Antonio R., Kahn, C. Ronald
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2016
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955986/
https://ncbi.nlm.nih.gov/pubmed/27207510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0213
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