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ATP-releasing Nucleotides: Linking DNA Synthesis to Luciferase Signaling
We report a new strategy to produce luminescence signals from DNA synthesis by designing chimeric nucleoside tetraphosphate dimers in which ATP, rather than pyrophosphate, is the leaving group. We describe the synthesis of ATP-releasing nucleotides (ARNs) as derivatives of the four canonical nucleot...
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| Veröffentlicht in: | Angew Chem Int Ed Engl |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4955596/ https://ncbi.nlm.nih.gov/pubmed/26836342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201509131 |
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