ω-3 PUFAs ameliorate liver fibrosis and inhibit hepatic stellate cells proliferation and activation by promoting YAP/TAZ degradation

Elevated levels of the transcriptional regulators Yes-associated protein (YAP) and transcriptional coactivators with PDZ-binding motif (TAZ), key effectors of the Hippo pathway, have been shown to play essential roles in controlling liver cell fate and the activation of hepatic stellate cells (HSCs)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Zhang, Kun, Chang, Yanan, Shi, Zhemin, Han, Xiaohui, Han, Yawei, Yao, Qingbin, Hu, Zhimei, Cui, Hongmei, Zheng, Lina, Han, Tao, Hong, Wei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951777/
https://ncbi.nlm.nih.gov/pubmed/27435808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30029
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