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Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis

Pancreatic ductal adenocarcinoma (PDAC) is characterized by a fibrotic and inflammatory microenvironment that is formed primarily by activated, myofibroblast-like, stellate cells. Although the stellate cells are thought to contribute to tumorigenesis, metastasis and drug resistance of PDAC, the sign...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Morvaridi, Susan, Dhall, Deepti, Greene, Mark I., Pandol, Stephen J., Wang, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645184/
https://ncbi.nlm.nih.gov/pubmed/26567630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16759
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