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What are the macrophages and stellate cells doing in pancreatic adenocarcinoma?

Pancreatic ductal adenocarcinoma is a devastating disease characterized by a dense desmoplastic stroma. Chemo- and radio-therapeutic strategies based on targeting cancer cells have failed in improving the outcome of this cancer suggesting important roles for stroma in therapy resistance. Cells in th...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Pandol, Stephen J., Edderkaoui, Mouad
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432577/
https://ncbi.nlm.nih.gov/pubmed/26029109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00125
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