ω-3 PUFAs ameliorate liver fibrosis and inhibit hepatic stellate cells proliferation and activation by promoting YAP/TAZ degradation

Elevated levels of the transcriptional regulators Yes-associated protein (YAP) and transcriptional coactivators with PDZ-binding motif (TAZ), key effectors of the Hippo pathway, have been shown to play essential roles in controlling liver cell fate and the activation of hepatic stellate cells (HSCs)...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Zhang, Kun, Chang, Yanan, Shi, Zhemin, Han, Xiaohui, Han, Yawei, Yao, Qingbin, Hu, Zhimei, Cui, Hongmei, Zheng, Lina, Han, Tao, Hong, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951777/
https://ncbi.nlm.nih.gov/pubmed/27435808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30029
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi