The liver-enriched lnc-LFAR1 promotes liver fibrosis by activating TGFβ and Notch pathways

Long noncoding RNAs (lncRNAs) play important roles in various biological processes such as proliferation, cell death and differentiation. Here, we show that a liver-enriched lncRNA, named liver fibrosis-associated lncRNA1 (lnc-LFAR1), promotes liver fibrosis. We demonstrate that lnc-LFAR1 silencing...

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書誌詳細
出版年:Nat Commun
主要な著者: Zhang, Kun, Han, Xiaohui, Zhang, Zhen, Zheng, Lina, Hu, Zhimei, Yao, Qingbin, Cui, Hongmei, Shu, Guiming, Si, Maojie, Li, Chan, Shi, Zhemin, Chen, Ting, Han, Yawei, Chang, Yanan, Yao, Zhi, Han, Tao, Hong, Wei
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529527/
https://ncbi.nlm.nih.gov/pubmed/28747678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00204-4
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