The liver-enriched lnc-LFAR1 promotes liver fibrosis by activating TGFβ and Notch pathways

Long noncoding RNAs (lncRNAs) play important roles in various biological processes such as proliferation, cell death and differentiation. Here, we show that a liver-enriched lncRNA, named liver fibrosis-associated lncRNA1 (lnc-LFAR1), promotes liver fibrosis. We demonstrate that lnc-LFAR1 silencing...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhang, Kun, Han, Xiaohui, Zhang, Zhen, Zheng, Lina, Hu, Zhimei, Yao, Qingbin, Cui, Hongmei, Shu, Guiming, Si, Maojie, Li, Chan, Shi, Zhemin, Chen, Ting, Han, Yawei, Chang, Yanan, Yao, Zhi, Han, Tao, Hong, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529527/
https://ncbi.nlm.nih.gov/pubmed/28747678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00204-4
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