PD-1 blockade enhances the vaccination-induced immune response in glioma

DC vaccination with autologous tumor lysate has demonstrated promising results for the treatment of glioblastoma (GBM) in preclinical and clinical studies. While the vaccine appears capable of inducing T cell infiltration into tumors, the effectiveness of active vaccination in progressively growing...

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Detalles Bibliográficos
Publicado en:JCI Insight
Main Authors: Antonios, Joseph P., Soto, Horacio, Everson, Richard G., Orpilla, Joey, Moughon, Diana, Shin, Namjo, Sedighim, Shaina, Yong, William H., Li, Gang, Cloughesy, Timothy F., Liau, Linda M., Prins, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951098/
https://ncbi.nlm.nih.gov/pubmed/27453950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87059
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