PD-1 blockade enhances the vaccination-induced immune response in glioma

DC vaccination with autologous tumor lysate has demonstrated promising results for the treatment of glioblastoma (GBM) in preclinical and clinical studies. While the vaccine appears capable of inducing T cell infiltration into tumors, the effectiveness of active vaccination in progressively growing...

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Dades bibliogràfiques
Publicat a:JCI Insight
Autors principals: Antonios, Joseph P., Soto, Horacio, Everson, Richard G., Orpilla, Joey, Moughon, Diana, Shin, Namjo, Sedighim, Shaina, Yong, William H., Li, Gang, Cloughesy, Timothy F., Liau, Linda M., Prins, Robert M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951098/
https://ncbi.nlm.nih.gov/pubmed/27453950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87059
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