PD-1 blockade enhances the vaccination-induced immune response in glioma

DC vaccination with autologous tumor lysate has demonstrated promising results for the treatment of glioblastoma (GBM) in preclinical and clinical studies. While the vaccine appears capable of inducing T cell infiltration into tumors, the effectiveness of active vaccination in progressively growing...

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Bibliografiska uppgifter
I publikationen:JCI Insight
Huvudupphovsmän: Antonios, Joseph P., Soto, Horacio, Everson, Richard G., Orpilla, Joey, Moughon, Diana, Shin, Namjo, Sedighim, Shaina, Yong, William H., Li, Gang, Cloughesy, Timothy F., Liau, Linda M., Prins, Robert M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951098/
https://ncbi.nlm.nih.gov/pubmed/27453950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87059
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