PD-1 blockade enhances the vaccination-induced immune response in glioma

DC vaccination with autologous tumor lysate has demonstrated promising results for the treatment of glioblastoma (GBM) in preclinical and clinical studies. While the vaccine appears capable of inducing T cell infiltration into tumors, the effectiveness of active vaccination in progressively growing...

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Библиографические подробности
Опубликовано в: :JCI Insight
Главные авторы: Antonios, Joseph P., Soto, Horacio, Everson, Richard G., Orpilla, Joey, Moughon, Diana, Shin, Namjo, Sedighim, Shaina, Yong, William H., Li, Gang, Cloughesy, Timothy F., Liau, Linda M., Prins, Robert M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2016
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951098/
https://ncbi.nlm.nih.gov/pubmed/27453950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87059
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