PD-1 blockade enhances the vaccination-induced immune response in glioma

DC vaccination with autologous tumor lysate has demonstrated promising results for the treatment of glioblastoma (GBM) in preclinical and clinical studies. While the vaccine appears capable of inducing T cell infiltration into tumors, the effectiveness of active vaccination in progressively growing...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Antonios, Joseph P., Soto, Horacio, Everson, Richard G., Orpilla, Joey, Moughon, Diana, Shin, Namjo, Sedighim, Shaina, Yong, William H., Li, Gang, Cloughesy, Timothy F., Liau, Linda M., Prins, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951098/
https://ncbi.nlm.nih.gov/pubmed/27453950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87059
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