Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans

According to the hygiene hypothesis, the increasing incidence of autoimmune diseases in western countries may be explained by changes in early microbial exposure, leading to altered immune maturation. We followed gut microbiome development from birth until age three in 222 infants in Northern Europe...

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Udgivet i:Cell
Main Authors: Vatanen, Tommi, Kostic, Aleksandar D., d’Hennezel, Eva, Siljander, Heli, Franzosa, Eric A., Yassour, Moran, Kolde, Raivo, Vlamakis, Hera, Arthur, Timothy D., Hämäläinen, Anu-Maaria, Peet, Aleksandr, Tillmann, Vallo, Uibo, Raivo, Mokurov, Sergei, Dorshakova, Natalya, Ilonen, Jorma, Virtanen, Suvi M., Szabo, Susanne J., Porter, Jeffrey A., Lähdesmäki, Harri, Huttenhower, Curtis, Gevers, Dirk, Cullen, Thomas W., Knip, Mikael, Xavier, Ramnik J.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950857/
https://ncbi.nlm.nih.gov/pubmed/27133167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.04.007
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