Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children

Viruses have long been considered potential triggers of autoimmune diseases. Here we defined the intestinal virome from birth to the development of autoimmunity in children at risk for type 1 diabetes (T1D). A total of 220 virus-enriched preparations from serially collected fecal samples from 11 chi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhao, Guoyan, Vatanen, Tommi, Droit, Lindsay, Park, Arnold, Kostic, Aleksandar D., Poon, Tiffany W., Vlamakis, Hera, Siljander, Heli, Härkönen, Taina, Hämäläinen, Anu-Maaria, Peet, Aleksandr, Tillmann, Vallo, Ilonen, Jorma, Wang, David, Knip, Mikael, Xavier, Ramnik J., Virgin, Herbert W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544325/
https://ncbi.nlm.nih.gov/pubmed/28696303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706359114
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