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Original Research: Diametric effects of hypoxia on pathophysiology of sickle cell disease in a murine model
Hypoxia causes erythrocyte sickling in vitro; however, its role in the pathophysiology of sickle cell disease is poorly understood. We report that hypoxia rapidly decreased oxygen saturation in transgenic sickle cell disease mice, but this effect was immediately buffered by a robust ventilatory resp...
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| Publicado no: | Exp Biol Med (Maywood) |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4950388/ https://ncbi.nlm.nih.gov/pubmed/27026725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370216642046 |
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