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Original Research: Diametric effects of hypoxia on pathophysiology of sickle cell disease in a murine model

Hypoxia causes erythrocyte sickling in vitro; however, its role in the pathophysiology of sickle cell disease is poorly understood. We report that hypoxia rapidly decreased oxygen saturation in transgenic sickle cell disease mice, but this effect was immediately buffered by a robust ventilatory resp...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Exp Biol Med (Maywood)
Päätekijät: Tan, Fang, Ghosh, Samit, Mosunjac, Mario, Manci, Elizabeth, Ofori-Acquah, Solomon Fiifi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: SAGE Publications 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950388/
https://ncbi.nlm.nih.gov/pubmed/27026725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370216642046
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