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The HIV glycan shield as a target for broadly neutralizing antibodies
The HIV envelope glycoprotein (Env) is the sole target for HIV broadly neutralizing antibodies (bnAbs). HIV Env is one of the most heavily glycosylated proteins known, with approximately half of its mass consisting of host‐derived N‐linked glycans. The high density of glycans creates a shield that i...
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| Pubblicato in: | FEBS J |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4950053/ https://ncbi.nlm.nih.gov/pubmed/26411545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13530 |
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