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The HIV glycan shield as a target for broadly neutralizing antibodies

The HIV envelope glycoprotein (Env) is the sole target for HIV broadly neutralizing antibodies (bnAbs). HIV Env is one of the most heavily glycosylated proteins known, with approximately half of its mass consisting of host‐derived N‐linked glycans. The high density of glycans creates a shield that i...

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Detalles Bibliográficos
Publicado en:FEBS J
Autor Principal: Doores, Katie J.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950053/
https://ncbi.nlm.nih.gov/pubmed/26411545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13530
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