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The HIV glycan shield as a target for broadly neutralizing antibodies

The HIV envelope glycoprotein (Env) is the sole target for HIV broadly neutralizing antibodies (bnAbs). HIV Env is one of the most heavily glycosylated proteins known, with approximately half of its mass consisting of host‐derived N‐linked glycans. The high density of glycans creates a shield that i...

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Dades bibliogràfiques
Publicat a:FEBS J
Autor principal: Doores, Katie J.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950053/
https://ncbi.nlm.nih.gov/pubmed/26411545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13530
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