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Gremlin-1 Overexpression in Mouse Lung Reduces Silica-Induced Lymphocyte Recruitment – A Link to Idiopathic Pulmonary Fibrosis through Negative Correlation with CXCL10 Chemokine

Idiopathic pulmonary fibrosis (IPF) is characterized by activation and injury of epithelial cells, the accumulation of connective tissue and changes in the inflammatory microenvironment. The bone morphogenetic protein (BMP) inhibitor protein gremlin-1 is associated with the progression of fibrosis b...

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Publicat a:PLoS One
Autors principals: Koli, Katri, Sutinen, Eva, Rönty, Mikko, Rantakari, Pia, Fortino, Vittorio, Pulkkinen, Ville, Greco, Dario, Sipilä, Petra, Myllärniemi, Marjukka
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948891/
https://ncbi.nlm.nih.gov/pubmed/27428020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159010
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