Gremlin-1 Overexpression in Mouse Lung Reduces Silica-Induced Lymphocyte Recruitment – A Link to Idiopathic Pulmonary Fibrosis through Negative Correlation with CXCL10 Chemokine

Idiopathic pulmonary fibrosis (IPF) is characterized by activation and injury of epithelial cells, the accumulation of connective tissue and changes in the inflammatory microenvironment. The bone morphogenetic protein (BMP) inhibitor protein gremlin-1 is associated with the progression of fibrosis b...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Koli, Katri, Sutinen, Eva, Rönty, Mikko, Rantakari, Pia, Fortino, Vittorio, Pulkkinen, Ville, Greco, Dario, Sipilä, Petra, Myllärniemi, Marjukka
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948891/
https://ncbi.nlm.nih.gov/pubmed/27428020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159010
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