Gremlin-1 Overexpression in Mouse Lung Reduces Silica-Induced Lymphocyte Recruitment – A Link to Idiopathic Pulmonary Fibrosis through Negative Correlation with CXCL10 Chemokine

Idiopathic pulmonary fibrosis (IPF) is characterized by activation and injury of epithelial cells, the accumulation of connective tissue and changes in the inflammatory microenvironment. The bone morphogenetic protein (BMP) inhibitor protein gremlin-1 is associated with the progression of fibrosis b...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Koli, Katri, Sutinen, Eva, Rönty, Mikko, Rantakari, Pia, Fortino, Vittorio, Pulkkinen, Ville, Greco, Dario, Sipilä, Petra, Myllärniemi, Marjukka
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948891/
https://ncbi.nlm.nih.gov/pubmed/27428020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159010
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