The Influence of Differentially Expressed Tissue-Type Plasminogen Activator in Experimental Autoimmune Encephalomyelitis: Implications for Multiple Sclerosis

Tissue type plasminogen activator (t-PA) has been implicated in the development of multiple sclerosis (MS) and in rodent models of experimental autoimmune encephalomyelitis (EAE). We show that levels of t-PA mRNA and activity are increased ~4 fold in the spinal cords of wild-type mice that are mice...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dahl, Lisa CM, Nasa, Zeyad, Chung, JieYu, Niego, Be’eri, Tarlac, Volga, Ho, Heidi, Galle, Adam, Petratos, Steven, Lee, Jae Young, Alderuccio, Frank, Medcalf, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948890/
https://ncbi.nlm.nih.gov/pubmed/27427941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158653
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