Limiting Neuronal Nogo Receptor 1 Signaling during Experimental Autoimmune Encephalomyelitis Preserves Axonal Transport and Abrogates Inflammatory Demyelination

We previously identified that ngr1 allele deletion limits the severity of experimental autoimmune encephalomyelitis (EAE) by preserving axonal integrity. However, whether this favorable outcome observed in EAE is a consequence of an abrogated neuronal-specific pathophysiological mechanism, is yet to...

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Publicat a:J Neurosci
Autors principals: Lee, Jae Young, Kim, Min Joung, Thomas, Speros, Oorschot, Viola, Ramm, Georg, Aui, Pei Mun, Sekine, Yuichi, Deliyanti, Devy, Wilkinson-Berka, Jennifer, Niego, Be'eri, Harvey, Alan R., Theotokis, Paschalis, McLean, Catriona, Strittmatter, Stephen M., Petratos, Steven
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616297/
https://ncbi.nlm.nih.gov/pubmed/31061088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1760-18.2019
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