Limiting Neuronal Nogo Receptor 1 Signaling during Experimental Autoimmune Encephalomyelitis Preserves Axonal Transport and Abrogates Inflammatory Demyelination

We previously identified that ngr1 allele deletion limits the severity of experimental autoimmune encephalomyelitis (EAE) by preserving axonal integrity. However, whether this favorable outcome observed in EAE is a consequence of an abrogated neuronal-specific pathophysiological mechanism, is yet to...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Lee, Jae Young, Kim, Min Joung, Thomas, Speros, Oorschot, Viola, Ramm, Georg, Aui, Pei Mun, Sekine, Yuichi, Deliyanti, Devy, Wilkinson-Berka, Jennifer, Niego, Be'eri, Harvey, Alan R., Theotokis, Paschalis, McLean, Catriona, Strittmatter, Stephen M., Petratos, Steven
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2019
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616297/
https://ncbi.nlm.nih.gov/pubmed/31061088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1760-18.2019
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