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Plasmin-dependent modulation of the blood–brain barrier: a major consideration during tPA-induced thrombolysis?
Plasmin, the principal downstream product of tissue-type plasminogen activator (tPA), is known for its potent fibrin-degrading capacity but is also recognized for many non-fibrinolytic activities. Curiously, plasmin has not been conclusively linked to blood–brain barrier (BBB) disruption during reco...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4126105/ https://ncbi.nlm.nih.gov/pubmed/24896566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.99 |
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