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tPA modulation of the blood-brain barrier: a unifying explanation for the pleiotropic effects of tPA in the CNS?
The plasminogen activation (PA) system is best known for its role in fibrinolysis. However, it has also been shown to regulate many non-fibrinolytic functions in the central nervous system (CNS). In particular, tissue-type plasminogen activator (tPA) is reported to have pleiotropic activities in the...
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| Publicado no: | Semin Thromb Hemost |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5848490/ https://ncbi.nlm.nih.gov/pubmed/27677179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0036-1586229 |
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