Highly sensitive and unbiased approach for elucidating antibody repertoires

Developing B lymphocytes undergo V(D)J recombination to assemble germ-line V, D, and J gene segments into exons that encode the antigen-binding variable region of Ig heavy (H) and light (L) chains. IgH and IgL chains associate to form the B-cell receptor (BCR), which, upon antigen binding, activates...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Lin, Sherry G., Ba, Zhaoqing, Du, Zhou, Zhang, Yu, Hu, Jiazhi, Alt, Frederick W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2016
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948367/
https://ncbi.nlm.nih.gov/pubmed/27354528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608649113
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