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Epithelial-mesenchymal transition is associated with a distinct tumor microenvironment including elevation of inflammatory signals and multiple immune checkpoints in lung adenocarcinoma

PURPOSE: Promising results in the treatment of NSCLC have been seen with agents targeting immune checkpoints, such as PD-1 or PD-L1. However, only a select group of patients respond to these interventions. The identification of biomarkers that predict clinical benefit to immune checkpoint blockade i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Clin Cancer Res
Egile Nagusiak: Lou, Yanyan, Diao, Lixia, Cuentas, Edwin Roger Parra, Denning, Warren L., Chen, Limo, Fan, Youhong, Byers, Lauren A., Wang, Jing, Papadimitrakopoulou, Vassiliki, Behrens, Carmen, Rodriguez, Jaime Canales, Hwu, Patrick, Wistuba, Ignacio I., Heymach, John V., Gibbons, Don L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947453/
https://ncbi.nlm.nih.gov/pubmed/26851185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1434
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