Image Analysis–based Assessment of PD-L1 and Tumor-Associated Immune Cells Density Supports Distinct Intratumoral Microenvironment Groups in Non–small Cell Lung Carcinoma Patients

PURPOSE: We investigated the correlation between immunohistochemical PD-L1 expression and tumor-associated immune cells (TAICs) density in non–small cell lung carcinoma (NSCLC) and correlated them with clinicopathologic variables. EXPERIMENTAL DESIGN: Tumor tissue specimens from 254 stage I–III NSCL...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Parra, Edwin R., Behrens, Carmen, Rodriguez-Canales, Jaime, Lin, Heather, Mino, Barbara, Blando, Jorge, Zhang, Jianjun, Gibbons, Don L., Heymach, John V., Sepesi, Boris, Swisher, Stephen G., Weissferdt, Annikka, Kalhor, Neda, Izzo, Julie, Kadara, Humam, Moran, Cesar, Lee, Jack J., Wistuba, Ignacio I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558040/
https://ncbi.nlm.nih.gov/pubmed/27252415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2443
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