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SIRT7 clears the way for DNA repair

Histone modification by reversible lysine acetylation is a key regulatory mechanism in chromatin and nuclear signaling, whose deregulation is linked to aging, cancer, and other diseases. New work by Vazquez et al (2016) uncovers a role for the sirtuin family deacetylase SIRT7, which controls epigene...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Paredes, Silvana, Chua, Katrin F
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946144/
https://ncbi.nlm.nih.gov/pubmed/27302089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201694904
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