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Generation and evaluation of Myostatin knock-out rabbits and goats using CRISPR/Cas9 system
Myostatin (Mstn) is a conserved negative regulator of skeletal muscle mass in mammals. However, whether precise disruption of Mstn in livestock can be achieved and safely used to improve meat productivity has not been proven. We applied CRISPR/Cas9 system to generate Mstn knock-out (KO) rabbits and...
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| Izdano u: | Sci Rep |
|---|---|
| Glavni autori: | , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4945924/ https://ncbi.nlm.nih.gov/pubmed/27417210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29855 |
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