Generation of beta-lactoglobulin knock-out goats using CRISPR/Cas9.
Goat's milk, considered a substitute for cow's milk, has a high nutritional value. However, goat's milk contains various allergens, predominantly β-lactoglobulin (BLG). In this study, we employed the CRISPR/Cas9 system to target the BLG locus in goat fibroblasts for sgRNA optimization...
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Hlavní autoři: | , , , , , , , |
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Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
Public Library of Science (PLoS)
2017-01-01
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Edice: | PLoS ONE |
On-line přístup: | http://europepmc.org/articles/PMC5634636?pdf=render |
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